Scientists have modified the antibiotic to make it more resistant to bacteria which can combat the antibiotic-resistant infections. The vancomycin drug is recommended by doctors to the patients and now the bacterias are becoming resistant to it.
The researchers from The Scripps Research Institute (TSRI) in the US have modified the vancomycin drug to fight the bacterias in three different ways. Basically, it makes it harder for the bacteria to develop resistance.
According to World Health Organization (WHO), antibiotic resistance is one of the major threat to health and security and development as major diseases are difficult to treat and drugs are becoming less effective due to increasing resistance.
If the drug resistance continues then this can cause 10million deaths every year. The time taken by bacteria to become resistant to drug shows how difficult it was to overcome the resistance and determine the formation of bacterial cell walls. Vancomycin was chosen as the experimental drug because it is magical antibiotic with high potency. Past studies have shown how the potency of the drug can be increased.
The new study published in the journal Proceedings of the National Academy of Sciences shows how the modified vancomycin drug interferes with the bacteria’s ability to form cell walls in a different manner. The modified vancomycin drug increases the drug activity by 100 times so doctors can use less antibiotic drugs to fight the infection.
The effectiveness of the drug was tested on Enterococci bacteria and the drug killed both the drug-resistant bacteria which is one of the largest threat to all living forms. Dale Boger, lead author of the study and co-chair of TSRI’s Department of Chemistry said the newly modified drug was highly beneficial in killing the bacteria using three ways.
Hence the scientists were successful in killing the Vancomycin-resistant drug Enterococci which is one of the threats to human health. In future, the scientists may develop new ways to create modified Vancomycin drug in a lab as the current method involves 30 steps.